Regional Prospective Observational Research for Tuberculosis

About Us

The Regional Prospective Observational Research in Tuberculosis (RePORT)-Brazil network was established in August, 2013 with funding from the Departamento de Ciência e Tecnologia (DECIT) – Secretaria de Ciência e Tecnologia (SCTIE) of the Ministry of Health of Brazil, and the National Institutes of Health of the United States.

Primary Objective:

To describe the clinical outcomes of TB treatment in Brazil, and the occurrence of M. tuberculosis infection and TB disease among close contacts of those TB source cases

Secondary Objectives:

  1. Create and maintain a biorepository of clinical specimens and a database of well-characterized clinical endpoints for the TB cases and their close contacts;
  2. Develop a scientific agenda that will utilize this specimen and data repository to improve our understanding of TB pathogenesis. This includes risk factors for M. tuberculosis infection, progression from latent M. tuberculosis infection to TB disease, and response to TB treatment. These studies may also lead to the identification of biomarkers of these important endpoints;
  3. Develop TB laboratory and clinical research infrastructure in Brazil.
This website is managed by the Coordinating Center at Vanderbilt University Medical Center.


For comments or questions, please contact:

Marina Cruvinel Figueiredo, Program Manager
Vanderbilt University Medical Center,


RePORT-Brazil acknowledges funding from the National Institutes of Health (NIH) (the National Institute of Allergy and Infectious Diseases (NIAID)), CRDF Global, Departamento de Ciencia e Tecnologia (DECIT)- Secretaria de Ciencia e Tecnologia (SCTIE) of the Ministry of Health of Brazil.