Salvador site

Salvador, Bahia

The José Silveira Foundation (FJS) and its Instituto Brasileiro de Investigação da Tuberculose (IBIT) together are a non-profit organization that was founded in 1937 in the State of Bahia/Brazil, and accredited by the government as a TB treatment center. IBIT founder Dr. Silveira built up a TB research program that has included participation in the research of the primary drugs and drug-schemes against tuberculosis. Currently, FJS/IBIT serves as a reference center for TB primary care and annually treats 10—15% of TB cases in the city of Salvador. This institute is part of the Brazilian National TB Control Program and follows all guidelines and recommendations of the Brazilian Society of Pulmonology and Tisiology, which are similar to WHO recommendations.

IBIT is a three story building of 780 m2 located close to other buildings of the FJS in the neighborhood of Federação. It has 4 rooms for clinical evaluations by physicians, two for nursing procedures, two for social support, one auditorium (80 seats), one meeting room (12 seats), a library, two rooms for food distribution, a waiting room, 4 large laboratories, 5 rooms for administration (shared with the whole administration of the Jose Silveira foundation), and three IT rooms.

  • First participant recruited in June 2016

    Bruno Bezerril Andrade, MD PhD

  • Population: DS-TB and TB close-contacts
  • Enrolled 583 participants to date (273 TB cases and 310 close contacts)
  • Micro Lab: IBIT, FJS / Immuno Lab: IGM, Fiocruz-BA

Microbiology Laboratory, IBIT – Salvador

  • Collaborator: Saulo Santos
  • Lab is responsible for processing all samples from the IBIT site
    • Over 270 TB patients from RePORT, with samples collected at Baseline, M1, M2 and end of treatment.
  • Evaluated by SMILE since 2013 (for RePORT)
  • External (SMILE, Westat) and internal (Lourenço) monitoring visits

Immunology Laboratory, IGM-FIOCRUZ Bahia

The Investigative Medicine Unit (IMU) is an advanced laboratory facility within the Laboratório Integrado de Microbiologia e Imunorregulação (LIMI) at the Centro de Pesquisas Gonçalo Moniz (CPqGM), Fundação Oswaldo Cruz (FIOCRUZ), located in Salvador.

  • Collaborator: Alice Andrade
  • Lab is responsible for processing all samples from the IBIT site
  • Over 580 participants from RePORT, with samples collected at Baseline, M1, M2 and end of treatment.
    • PBMCs and QuantiFERON, as well as plasma, urine, RNA, etc.
  • Evaluated by Duke University since June 2015
  • QuantiFERON training
  • External (Westat) monitoring visits

Site team:
Site Investigator: Bruno Andrade
Study Coordinator: Michael Rocha
Study Nurse: Vanessa Nascimento
Study Physician: Betania Nogueira
Immunology Lab: Alice Andrade
Microbiology Lab: Saulo Santos