The Regional Prospective Observational Research in Tuberculosis (RePORT)-Brazil network was established in August, 2013 with funding from the Departamento de Ciência e Tecnologia (DECIT) – Secretaria de Ciência e Tecnologia (SCTIE) of the Ministry of Health of Brazil, and the National Institutes of Health of the United States.
The primary objective of RePORT-Brazil is to describe the clinical outcomes of TB treatment in Brazil, and the occurrence of M. tuberculosis infection and TB disease among close contacts of those TB source cases. Other objectives include: the creation and maintenance of a biorepository of clinical specimens and a database of well-characterized clinical endpoints for the TB cases and their close contacts; the development of a scientific agenda that will utilize this specimen and data repository to improve our understanding of TB pathogenesis; and develop TB laboratory and clinical research infrastructure in Brazil.